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TCF4 Antibody

Product Specifications

Background

TCF4 is transcription factor 4, a basic helix-turn-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is expressed predominantly in pre-B-cells, although it is found in other tissues as well. Defects in this gene are a cause of Pitt-Hopkins syndrome.

NCBI Gene ID

6925

Swiss Prot

P15884

Accession Number

P15884

Host

Rabbit

Reactivity

Human

Immunogen

This TCF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-73 amino acids from the N-terminal region of human TCF4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

71 kDa

Fragment

Rabbit Ig

Symbol

TCF4

NCBI Official Name

Transcription factor 4

NCBI Organism

Homo sapiens

Background Reference 01

Rosenfeld, J.A., et al. Genet. Med. 11 (11) :797-805 (2009)

Background Reference 02

Herbst, A., et al. Biochem. Biophys. Res. Commun. 387 (4) :736-740 (2009)

Background Reference 03

Rena, V., et al. Placenta 30 (10) :876-883 (2009)

Background Reference 04

Henthorn, P., et al. Science 247 (4941) :467-470 (1990)

Other Product Names

Transcription factor 4, TCF-4, Class B basic helix-loop-helix protein 19, bHLHb19, Immunoglobulin transcription factor 2, ITF-2, SL3-3 enhancer factor 2, SEF-2, TCF4, BHLHB19, ITF2, SEF2

Tested Applications

WB, Flow

Physical Properties

Liquid

Frequently Asked Questions

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