TCF4 Antibody
Product Specifications
Background
TCF4 is transcription factor 4, a basic helix-turn-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is expressed predominantly in pre-B-cells, although it is found in other tissues as well. Defects in this gene are a cause of Pitt-Hopkins syndrome.
NCBI Gene ID
6925
Swiss Prot
P15884
Accession Number
P15884
Host
Rabbit
Reactivity
Human
Immunogen
This TCF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-73 amino acids from the N-terminal region of human TCF4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
71 kDa
Fragment
Rabbit Ig
Symbol
TCF4
NCBI Official Name
Transcription factor 4
NCBI Organism
Homo sapiens
Background Reference 01
Rosenfeld, J.A., et al. Genet. Med. 11 (11) :797-805 (2009)
Background Reference 02
Herbst, A., et al. Biochem. Biophys. Res. Commun. 387 (4) :736-740 (2009)
Background Reference 03
Rena, V., et al. Placenta 30 (10) :876-883 (2009)
Background Reference 04
Henthorn, P., et al. Science 247 (4941) :467-470 (1990)
Other Product Names
Transcription factor 4, TCF-4, Class B basic helix-loop-helix protein 19, bHLHb19, Immunoglobulin transcription factor 2, ITF-2, SL3-3 enhancer factor 2, SEF-2, TCF4, BHLHB19, ITF2, SEF2
Tested Applications
WB, Flow
Physical Properties
Liquid
Frequently Asked Questions
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