LCLT1 Antibody
Product Specifications
Background
Acyl-CoA:lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial lineages.
NCBI Gene ID
253558
Swiss Prot
Q6UWP7
Accession Number
Q6UWP7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This LCLT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-324 amino acids from the C-terminal region of human LCLT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=62-021
Calculated Molecular Weight
49 kDa
Fragment
Rabbit Ig
Symbol
LCLAT1
NCBI Official Name
Lysocardiolipin acyltransferase 1
NCBI Organism
Homo sapiens
Background Reference 01
Zhao, Y., et al. J. Lipid Res. 50 (5) :945-956 (2009)
Background Reference 02
Wang, C., et al. Blood 110 (10) :3601-3609 (2007)
Background Reference 03
Agarwal, A.K., et al. Arch. Biochem. Biophys. 449 (1-2), 64-76 (2006)
Other Product Names
Lysocardiolipin acyltransferase 1, 231-, 1-acylglycerol-3-phosphate O-acyltransferase 8, 1-AGP acyltransferase 8, 1-AGPAT 8, Acyl-CoA:lysocardiolipin acyltransferase 1, LCLAT1, AGPAT8, ALCAT1, LYCAT
Tested Applications
WB, IHC-P
Protein ID
74749398
Physical Properties
Liquid
Curated Selection
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