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RSPO4 Antibody

Product Specifications

Background

RSPO4 is a member of the R-spondin family of proteins that share a common domain organization consisting of a signal peptide, cysteine-rich/furin-like domain, thrombospondin domain and a C-terminal basic region. The encoded protein may be involved in activation of Wnt/beta-catenin signaling pathways. Mutations in this gene are associated with anonychia congenital. Alternate splicing results in multiple transcript variants.

NCBI Gene ID

343637

Swiss Prot

Q2I0M5

Accession Number

Q2I0M5

Host

Rabbit

Reactivity

Human

Immunogen

This RSPO4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-228 amino acids from the C-terminal region of human RSPO4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

26 kDa

Fragment

Rabbit Ig

Symbol

RSPO4

NCBI Official Name

R-spondin-4

NCBI Organism

Homo sapiens

Background Reference 01

Bergmann, C., et al. Am. J. Hum. Genet. 79 (6) :1105-1109 (2006)

Background Reference 02

Blaydon, D.C., et al. Nat. Genet. 38 (11) :1245-1247 (2006)

Background Reference 03

Kim, K.A., et al. Cell Cycle 5 (1) :23-26 (2006)

Other Product Names

R-spondin-4, Roof plate-specific spondin-4, hRspo4, RSPO4, C20orf182

Tested Applications

WB, IHC-P, Flow

Protein ID

97189858

Physical Properties

Liquid

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