RSPO4 Antibody
Product Specifications
Background
RSPO4 is a member of the R-spondin family of proteins that share a common domain organization consisting of a signal peptide, cysteine-rich/furin-like domain, thrombospondin domain and a C-terminal basic region. The encoded protein may be involved in activation of Wnt/beta-catenin signaling pathways. Mutations in this gene are associated with anonychia congenital. Alternate splicing results in multiple transcript variants.
NCBI Gene ID
343637
Swiss Prot
Q2I0M5
Accession Number
Q2I0M5
Host
Rabbit
Reactivity
Human
Immunogen
This RSPO4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-228 amino acids from the C-terminal region of human RSPO4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
26 kDa
Fragment
Rabbit Ig
Symbol
RSPO4
NCBI Official Name
R-spondin-4
NCBI Organism
Homo sapiens
Background Reference 01
Bergmann, C., et al. Am. J. Hum. Genet. 79 (6) :1105-1109 (2006)
Background Reference 02
Blaydon, D.C., et al. Nat. Genet. 38 (11) :1245-1247 (2006)
Background Reference 03
Kim, K.A., et al. Cell Cycle 5 (1) :23-26 (2006)
Other Product Names
R-spondin-4, Roof plate-specific spondin-4, hRspo4, RSPO4, C20orf182
Tested Applications
WB, IHC-P, Flow
Protein ID
97189858
Physical Properties
Liquid
Curated Selection
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