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WNT5A Antibody

Product Specifications

Background

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98%, 98% and 87% amino acid identity to the mouse, rat and the xenopus Wnt5A protein, respectively. The experiments performed in Xenopus laevis embryos identified that human frizzled-5 (hFz5) is the receptor for the Wnt5A ligand and the Wnt5A/hFz5 signaling mediates axis induction. [provided by RefSeq].

NCBI Gene ID

7474

Swiss Prot

P41221

Accession Number

P41221

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This WNT5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-213 amino acids from the Central region of human WNT5A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rabbit

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=62-006

Calculated Molecular Weight

42 kDa

Fragment

Rabbit Ig

Symbol

WNT5A

NCBI Official Name

Protein Wnt-5a

NCBI Organism

Homo sapiens

Background Reference 01

He, X., et al. Science 275 (5306) :1652-1654 (1997)

Background Reference 02

Danielson, K.G., et al. J. Biol. Chem. 270 (52) :31225-31234 (1995)

Background Reference 03

Smolich, B.D., et al. Mol. Biol. Cell 4 (12) :1267-1275 (1993)

Background Reference 04

Clark, C.C., et al. Genomics 18 (2) :249-260 (1993)

Other Product Names

Protein Wnt-5a, WNT5A

Tested Applications

WB, IHC-P, Flow

Protein ID

212276478

Physical Properties

Liquid

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