STX7 Antibody
Product Specifications
Background
Syntaxin 7 is involved in the ordered fusion of endosomes and lysosomes with the phagosome, where phagocytic cells kill and degrade internalized foreign particles. Syntaxin 7 is found in late endosomes and lysosomes; whereas Syntaxin 12 is localized to the recycling endosome compartment, both are recruited to the phagosome. However, STX12 is acquired earlier before rapidly recycling off the phagosome, whereas STX7 is recruited later and continues to accumulate throughout the phagosome maturation process.
NCBI Gene ID
8417
Swiss Prot
O15400
Accession Number
O15400
Host
Rabbit
Reactivity
Human
Immunogen
This STX7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47-73 amino acids from the N-terminal region of human STX7.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
30 kDa
Fragment
Rabbit Ig
Symbol
STX7
NCBI Official Name
Syntaxin-7
NCBI Organism
Homo sapiens
Background Reference 01
Prekeris, R., et al. Mol. Biol. Cell 10 (11) :3891-3908 (1999)
Background Reference 02
Steegmaier, M., et al. J. Biol. Chem. 273 (51) :34171-34179 (1998)
Background Reference 03
Wong, S.H., et al. J. Biol. Chem. 273 (1) :375-380 (1998)
Background Reference 04
Wang, H., et al. Gene 199 (1-2), 39-48 (1997)
Other Product Names
Syntaxin-7, STX7
Tested Applications
WB, IHC-P, Flow
Physical Properties
Liquid
Curated Selection
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