TRHDE Antibody

Product Specifications

Background

This gene encodes a member of the peptidase M1 family. TRHDE is an extracellular peptidase that specifically cleaves and inactivates the neuropeptide thyrotropin-releasing hormone.

NCBI Gene ID

29953

Swiss Prot

Q9UKU6

Accession Number

Q9UKU6

Host

Rabbit

Reactivity

Human

Immunogen

This TRHDE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 951-980 amino acids from the C-terminal region of human TRHDE.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

117 kDa

Fragment

Rabbit Ig

Symbol

TRHDE

NCBI Official Name

Thyrotropin-releasing hormone-degrading ectoenzyme

NCBI Organism

Homo sapiens

Background Reference 01

Cirulli, E.T., et al. Eur. J. Hum. Genet. (2010) In press :

Background Reference 02

Murabito, J.M., et al. BMC Med. Genet.SUPPL 1, S6 (2007) :

Background Reference 03

Schomburg, L., et al. Eur. J. Biochem. 265 (1) :415-422 (1999)

Background Reference 04

Bodeker, H., et al. Mol. Cell Biol. Res. Commun. 2 (3) :150-154 (1999)

Other Product Names

Thyrotropin-releasing hormone-degrading ectoenzyme, TRH-DE, TRH-degrading ectoenzyme, Pyroglutamyl-peptidase II, PAP-II, TRH-specific aminopeptidase, Thyroliberinase, TRHDE