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BLOC1S2 Antibody

Product Specifications

Background

BLOC1S2 is a component of the ubiquitously expressed BLOC1 multisubunit protein complex. BLOC1 is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules (Starcevic and Dell'Angelica, 2004 [PubMed 15102850]) .

NCBI Gene ID

282991

Swiss Prot

Q6QNY1

Accession Number

Q6QNY1

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This BLOC1S2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-40 amino acids from the Central region of human BLOC1S2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

16 kDa

Fragment

Rabbit Ig

Symbol

BLOC1S2

NCBI Official Name

Biogenesis of lysosome-related organelles complex 1 subunit 2

NCBI Organism

Homo sapiens

Background Reference 01

Rodriguez-Fernandez, I.A., et al. J. Inherit. Metab. Dis. 32 (2) :190-203 (2009)

Background Reference 02

Gdynia, G., et al. Apoptosis 13 (3) :437-447 (2008)

Background Reference 03

Wang, Z., et al. J. Mol. Biol. 343 (1) :71-82 (2004)

Other Product Names

Biogenesis of lysosome-related organelles complex 1 subunit 2, BLOC-1 subunit 2, Centrosome-associated protein, BLOC1S2, BLOS2, CEAP

Tested Applications

WB, IHC-P, Flow

Protein ID

74749300

Physical Properties

Liquid

Frequently Asked Questions

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