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AHR Antibody

Product Specifications

Background

AHR is a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Its ligands included a variety of aromatic hydrocarbons. [provided by RefSeq].

NCBI Gene ID

196

Swiss Prot

P35869

Accession Number

P35869

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This AHR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 555-582 amino acids from the Central region of human AHR.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

96 kDa

Fragment

Rabbit Ig

Symbol

AHR

NCBI Official Name

Aryl hydrocarbon receptor

NCBI Organism

Homo sapiens

Background Reference 01

Davila, S., et al. Genes Immun. (2010) In press :

Background Reference 02

Kalthoff, S., et al. J. Biol. Chem. 285 (9) :5993-6002 (2010)

Background Reference 03

Hall, J.M., et al. Mol. Endocrinol. 24 (2) :359-369 (2010)

Background Reference 04

Schroeder, J.C., et al. Biochemistry 49 (2) :393-400 (2010)

Other Product Names

Aryl hydrocarbon receptor, Ah receptor, AhR, Class E basic helix-loop-helix protein 76, bHLHe76, AHR, BHLHE76

Tested Applications

WB, IHC-P, IF, Flow

Protein ID

3041653

Physical Properties

Liquid

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