TREM2 Antibody
Product Specifications
Background
TREM2 is a membrane protein that forms a receptor signaling complex with TYROBP. The encoded protein may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL) .
NCBI Gene ID
54209
Swiss Prot
Q9NZC2
Accession Number
Q9NZC2
Host
Rabbit
Reactivity
Human
Immunogen
This TREM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-50 amino acids from the N-terminal region of human TREM2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
25 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TREM2
NCBI Official Name
Triggering receptor expressed on myeloid cells 2
NCBI Organism
Homo sapiens
Background Reference 01
Stefano, L., et al. J. Neurochem. 110 (1) :284-294 (2009)
Background Reference 02
Ford, J.W., et al. Curr. Opin. Immunol. 21 (1) :38-46 (2009)
Other Product Names
Triggering receptor expressed on myeloid cells 2, TREM-2, Triggering receptor expressed on monocytes 2, TREM2
Tested Applications
WB
Protein ID
50401689
Physical Properties
Liquid
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