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PGD Antibody

Product Specifications

Background

6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies.

NCBI Gene ID

5226

Swiss Prot

P52209

Accession Number

P52209

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This PGD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-265 amino acids from the Central region of human PGD.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Pig, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=61-935

Calculated Molecular Weight

53 kDa

Fragment

Rabbit Ig

Symbol

PGD

NCBI Official Name

6-phosphogluconate dehydrogenase, decarboxylating

NCBI Organism

Homo sapiens

Background Reference 01

Lehner, B., et al. Genome Res. 14 (7) :1315-1323 (2004)

Background Reference 02

Kerimov, B.F. Vopr. Med. Khim. 48 (5) :490-496 (2002)

Background Reference 03

Rippa, M., et al. Biochim. Biophys. Acta 1429 (1) :83-92 (1998)

Other Product Names

6-phosphogluconate dehydrogenase, decarboxylating, PGD, PGDH

Tested Applications

WB, IHC-P, Flow

Protein ID

20981679

Physical Properties

Liquid

Curated Selection

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