DCLRE1B Antibody
Product Specifications
Background
DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000 [PubMed 10848582]) .
NCBI Gene ID
64858
Swiss Prot
Q9H816
Accession Number
Q9H816
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This DCLRE1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-236 amino acids from the Central region of human DCLRE1B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=61-924
Calculated Molecular Weight
60 kDa
Fragment
Rabbit Ig
Symbol
DCLRE1B
NCBI Official Name
5' exonuclease Apollo
NCBI Organism
Homo sapiens
Background Reference 01
Anders, M., et al. Cell Cycle 8 (11) :1725-1732 (2009) Liu, L., et al. Cell Cycle 8 (4) :628-638 (2009) Freibaum, B.D., et al. J. Biol. Chem. 283 (35) :23671-23676 (2008) Bae, J.B., et al. Oncogene 27 (37) :5045-5056 (2008) Demuth, I., et al. DNA Repair (Amst.) 7 (8) :1192-1201 (2008) Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007) Lenain, C., et al. Curr. Biol. 16 (13) :1303-1310 (2006) Freibaum, B.D., et al. J. Biol. Chem. 281 (22) :15033-15036 (2006) Ishiai, M., et al. Mol. Cell. Biol. 24 (24) :10733-10741 (2004) Demuth, I., et al. Oncogene 23 (53) :8611-8618 (2004) Dronkert, M.L., et al. Mol. Cell. Biol. 20 (13) :4553-4561 (2000)
Other Product Names
5' exonuclease Apollo, 31--, DNA cross-link repair 1B protein, SNM1 homolog B, SNMIB, hSNM1B, DCLRE1B, SNM1B
Tested Applications
WB, IHC-P
Protein ID
73620756
Physical Properties
Liquid
Curated Selection
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