DCLRE1B Antibody

Product Specifications

Background

DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000 [PubMed 10848582]) .

NCBI Gene ID

64858

Swiss Prot

Q9H816

Accession Number

Q9H816

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This DCLRE1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-236 amino acids from the Central region of human DCLRE1B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

60 kDa

Fragment

Rabbit Ig

Symbol

DCLRE1B

NCBI Official Name

5' exonuclease Apollo

NCBI Organism

Homo sapiens

Background Reference 01

Anders, M., et al. Cell Cycle 8 (11) :1725-1732 (2009) Liu, L., et al. Cell Cycle 8 (4) :628-638 (2009) Freibaum, B.D., et al. J. Biol. Chem. 283 (35) :23671-23676 (2008) Bae, J.B., et al. Oncogene 27 (37) :5045-5056 (2008) Demuth, I., et al. DNA Repair (Amst.) 7 (8) :1192-1201 (2008) Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007) Lenain, C., et al. Curr. Biol. 16 (13) :1303-1310 (2006) Freibaum, B.D., et al. J. Biol. Chem. 281 (22) :15033-15036 (2006) Ishiai, M., et al. Mol. Cell. Biol. 24 (24) :10733-10741 (2004) Demuth, I., et al. Oncogene 23 (53) :8611-8618 (2004) Dronkert, M.L., et al. Mol. Cell. Biol. 20 (13) :4553-4561 (2000)