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PTAFR Antibody

Product Specifications

Background

PTAFR shows structural characteristics of the rhodopsin (MIM 180380) gene family and binds platelet-activating factor (PAF) . PAF is a phospholipid (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) that has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes.

NCBI Gene ID

5724

Swiss Prot

P25105

Accession Number

P25105

Host

Rabbit

Reactivity

Human

Immunogen

This PTAFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-312 amino acids from the C-terminal region of human PTAFR.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=61-919

Calculated Molecular Weight

39 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PTAFR

NCBI Official Name

Platelet-activating factor receptor

NCBI Organism

Homo sapiens

Background Reference 01

Davila, S., et al. Genes Immun. (2010) In press :

Background Reference 02

Hirota, N., et al. J. Biol. Chem. 285 (8) :5931-5940 (2010)

Background Reference 03

Kaneko, K., et al. J. Invest. Dermatol. 129 (11) :2567-2573 (2009)

Background Reference 04

Melnikova, V.O., et al. J. Biol. Chem. 284 (42) :28845-28855 (2009)

Other Product Names

Platelet-activating factor receptor, PAF-R, PAFr, PTAFR, PAFR

Tested Applications

WB

Protein ID

129557

Physical Properties

Liquid

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