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PYHIN1 Antibody

Product Specifications

Background

PYHIN1 belongs to the HIN200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-terminal ends. HIN200 proteins are primarily nuclear and are involved in transcriptional regulation of genes important for cell cycle control, differentiation, and apoptosis (Ding et al., 2006 [PubMed 16479015]) .

NCBI Gene ID

149628

Swiss Prot

Q6K0P9

Accession Number

Q6K0P9

Host

Rabbit

Reactivity

Human

Immunogen

This PYHIN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human PYHIN1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

55 kDa

Fragment

Rabbit Ig

Symbol

PYHIN1

NCBI Official Name

Pyrin and HIN domain-containing protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Yamaguchi, H., et al. Mol. Carcinog. 47 (10) :739-743 (2008)

Background Reference 02

Ding, Y., et al. Mol. Cell. Biol. 26 (5) :1979-1996 (2006)

Background Reference 03

Ding, Y., et al. Oncogene 23 (26) :4556-4566 (2004)

Other Product Names

Pyrin and HIN domain-containing protein 1, Interferon-inducible protein X, PYHIN1, IFIX

Tested Applications

WB, IHC-P, Flow

Protein ID

74748871

Physical Properties

Liquid

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