PYHIN1 Antibody
Product Specifications
Background
PYHIN1 belongs to the HIN200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-terminal ends. HIN200 proteins are primarily nuclear and are involved in transcriptional regulation of genes important for cell cycle control, differentiation, and apoptosis (Ding et al., 2006 [PubMed 16479015]) .
NCBI Gene ID
149628
Swiss Prot
Q6K0P9
Accession Number
Q6K0P9
Host
Rabbit
Reactivity
Human
Immunogen
This PYHIN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human PYHIN1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
55 kDa
Fragment
Rabbit Ig
Symbol
PYHIN1
NCBI Official Name
Pyrin and HIN domain-containing protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Yamaguchi, H., et al. Mol. Carcinog. 47 (10) :739-743 (2008)
Background Reference 02
Ding, Y., et al. Mol. Cell. Biol. 26 (5) :1979-1996 (2006)
Background Reference 03
Ding, Y., et al. Oncogene 23 (26) :4556-4566 (2004)
Other Product Names
Pyrin and HIN domain-containing protein 1, Interferon-inducible protein X, PYHIN1, IFIX
Tested Applications
WB, IHC-P, Flow
Protein ID
74748871
Physical Properties
Liquid
Curated Selection
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