FADS2 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.

NCBI Gene ID

9415

Swiss Prot

O95864

Accession Number

O95864

Host

Rabbit

Reactivity

Human

Immunogen

This FADS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-122 amino acids from the Central region of human FADS2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Xenopus

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

52 kDa

Fragment

Rabbit Ig

Symbol

FADS2

NCBI Official Name

Fatty acid desaturase 2

NCBI Organism

Homo sapiens

Background Reference 01

Molto-Puigmarti, C., et al. Am. J. Clin. Nutr. (2010) In press :

Background Reference 02

Lattka, E., et al. Curr. Opin. Lipidol. 21 (1) :64-69 (2010)

Background Reference 03

Lattka, E., et al. J. Lipid Res. 51 (1) :182-191 (2010)

Background Reference 04

Glaser, C., et al. Metab. Clin. Exp. (2009) In press :

Other Product Names

Fatty acid desaturase 2, 11419-, Delta (6) fatty acid desaturase, D6D, Delta (6) desaturase, Delta-6 desaturase, FADS2

Tested Applications

WB, IHC-P, Flow

Physical Properties

Liquid

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