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UBAC1 Antibody

Product Specifications

Background

UBAC1 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein has two RRM domains that bind to RNAs.

NCBI Gene ID

10422

Swiss Prot

Q9BSL1

Accession Number

Q9BSL1

Host

Rabbit

Reactivity

Human

Immunogen

This UBAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 264-292 amino acids from the C-terminal region of human UBAC1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

45 kDa

Fragment

Rabbit Ig

Symbol

UBAC1

NCBI Official Name

Ubiquitin-associated domain-containing protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Walker, L.C., et al. Breast Cancer Res. Treat. 112 (2) :229-236 (2008)

Background Reference 02

Wu, Y.Y., et al. Cell Biochem. Funct. 26 (4) :467-477 (2008)

Background Reference 03

Reboll, M.R., et al. RNA 13 (8) :1328-1340 (2007)

Other Product Names

Ubiquitin-associated domain-containing protein 1, UBA domain-containing protein 1, E3 ubiquitin-protein ligase subunit KPC2, Glialblastoma cell differentiation-related protein 1, Kip1 ubiquitination-promoting complex protein 2, UBAC1, GBDR1, KPC2, UBADC1

Tested Applications

WB, IHC-P, Flow

Protein ID

74752306

Physical Properties

Liquid

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