CD63 Antibody
Product Specifications
Background
CD63 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. The use of alternate polyadenylation sites has been found for this gene.
NCBI Gene ID
967
Swiss Prot
P08962
Accession Number
P08962
Host
Rabbit
Reactivity
Human
Immunogen
This CD63 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-190 amino acids from the C-terminal region of human CD63.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=61-885
Calculated Molecular Weight
26 kDa
Fragment
Rabbit Ig
Symbol
CD63
NCBI Official Name
CD63 antigen
NCBI Organism
Homo sapiens
Background Reference 01
Weng, J., et al. J. Virol. 83 (15) :7467-7474 (2009)
Background Reference 02
Kassahn, D., et al. Cell Death Differ. 16 (1) :115-124 (2009)
Background Reference 03
Logozzi, M., et al. PLoS ONE (4), E5219 (2009)
Other Product Names
CD63 antigen, Granulophysin, Lysosomal-associated membrane protein 3, LAMP-3, Melanoma-associated antigen ME491, OMA81H, Ocular melanoma-associated antigen, Tetraspanin-30, Tspan-30, CD63, CD63, MLA1, TSPAN30
Tested Applications
WB, IHC-P, Flow
Protein ID
116026
Physical Properties
Liquid
Curated Selection
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