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Tnks 2 Antibody

Product Specifications

Background

Tnks 2 may regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. Tnks 2 has PARP activity and can modify TRF1, and thereby contribute to the regulation of telomere length.

NCBI Gene ID

80351

Swiss Prot

Q9H2K2

Accession Number

Q9H2K2

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Tnks 2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1126-1156 amino acids from the C-terminal region of human Tnks 2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=61-877

Calculated Molecular Weight

127 kDa

Fragment

Rabbit Ig

Symbol

TNKS2

NCBI Official Name

Tankyrase-2

NCBI Organism

Homo sapiens

Background Reference 01

Varadi, V., et al. Eur. J. Cancer 45 (17) :3008-3016 (2009)

Background Reference 02

Shebzukhov, Y.V., et al. Cancer Immunol. Immunother. 57 (6) :871-881 (2008)

Background Reference 03

Sidorova, N.N., et al. Biochemistry Mosc. 73 (3) :289-295 (2008)

Other Product Names

Tankyrase-2, TANK2, ADP-ribosyltransferase diphtheria toxin-like 6, ARTD6, Poly [ADP-ribose] polymerase 5B, TNKS-2, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, Tankyrase II, Tankyrase-like protein, Tankyrase-related protein, TNKS2, PARP5B, TANK2, TNKL

Tested Applications

WB, Flow

Protein ID

20140805

Physical Properties

Liquid

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