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RPA43 Antibody

Product Specifications

Background

RPA43 is DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. It is component of RNA polymerase I which synthesizes ribosomal RNA precursors. Through its association with RRN3/TIF-IA may be involved in recruitment of Pol I to rDNA promoters.

NCBI Gene ID

221830

Swiss Prot

Q3B726

Accession Number

Q3B726

Host

Rabbit

Reactivity

Human

Immunogen

This RPA43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-326 amino acids from the C-terminal region of human RPA43.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

37 kDa

Fragment

Rabbit Ig

Symbol

TWISTNB

NCBI Official Name

DNA-directed RNA polymerase I subunit RPA43

NCBI Organism

Homo sapiens

Background Reference 01

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Background Reference 02

Yuan, X., et al. EMBO Rep. 3 (11) :1082-1087 (2002)

Background Reference 03

Kosan, C., et al. Cytogenet. Genome Res. 97 (3-4), 167-170 (2002)

Other Product Names

DNA-directed RNA polymerase I subunit RPA43, Twist neighbor protein, TWISTNB

Tested Applications

WB, IHC-P

Protein ID

121942339

Physical Properties

Liquid

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