MFRN2 Antibody

Product Specifications

Background

MFRN2 is mitochondrial iron transporter that mediates iron uptake. It is probably required for heme synthesis of hemoproteins and Fe-S cluster assembly in non-erythroid cells. The iron delivered into the mitochondria, presumably as Fe (2+), is then probably delivered to ferrochelatase to catalyze Fe (2+) incorporation into protoprophyrin IX to make heme.

NCBI Gene ID

81894

Swiss Prot

Q96A46

Accession Number

Q96A46

Host

Rabbit

Reactivity

Human

Immunogen

This MFRN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the N-terminal region of human MFRN2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

39 kDa

Fragment

Rabbit Ig

Symbol

SLC25A28

NCBI Official Name

Mitoferrin-2

NCBI Organism

Homo sapiens

Background Reference 01

Grupe, A., et al. Am. J. Hum. Genet. 78 (1) :78-88 (2006)

Background Reference 02

Deloukas, P., et al. Nature 429 (6990) :375-381 (2004)

Background Reference 03

Wistow, G., et al. Mol. Vis. 8, 185-195 (2002)

Other Product Names

Mitoferrin-2, Mitochondrial RNA-splicing protein 3/4 homolog, MRS3/4, hMRS3/4, Mitochondrial iron transporter 2, Solute carrier family 25 member 28, SLC25A28, MFRN2