ERO1LB Antibody

Product Specifications

Background

ERO1LB is essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. ERO1LB acts by oxidizing directly P4HB/PDI isomerase through a direct disulfide exchange. ERO1LB does not act as a direct oxidant of folding substrate, but relies on P4HB/PDI to transfer oxidizing equivalent.

NCBI Gene ID

56605

Swiss Prot

Q86YB8

Accession Number

Q86YB8

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This ERO1LB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-293 amino acids from the C-terminal region of human ERO1LB.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

54 kDa

Fragment

Rabbit Ig

Symbol

ERO1LB

NCBI Official Name

ERO1-like protein beta

NCBI Organism

Homo sapiens

Background Reference 01

Landa, I., et al. PLoS Genet. (9), E1000637 (2009) Savu, M.K., et al. Surg Obes Relat Dis 5 (2) :172-180 (2009) Tavendale, R., et al. J. Allergy Clin. Immunol. 121 (4) :860-863 (2008)