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CNO6L Antibody

Product Specifications

Background

CNO6L plays a role in the deadenylation of mRNAs in the cytoplasm. CNO6L has 3'-5' poly (A) exoribonuclease activity for synthetic poly (A) RNA substrate. CNO6L may be involved in the deadenylation-dependent degradation of mRNAs through the 3'-UTR AU-rich element-mediated mechanism. This protein involved in deadenylation-dependent degradation of CDKN1B mRNA.

NCBI Gene ID

246175

Swiss Prot

Q96LI5

Accession Number

Q96LI5

Host

Rabbit

Reactivity

Human

Immunogen

This CNO6L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-442 amino acids from the C-terminal region of human CNO6L.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Xenopus

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

63 kDa

Fragment

Rabbit Ig

Symbol

CNOT6L

NCBI Official Name

CCR4-NOT transcription complex subunit 6-like

NCBI Organism

Homo sapiens

Background Reference 01

Miyasaka, T., et al. Cancer Sci. 99 (4) :755-761 (2008)

Background Reference 02

Morita, M., et al. Mol. Cell. Biol. 27 (13) :4980-4990 (2007)

Background Reference 03

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007)

Other Product Names

CNOT6L; CCR4B; CCR4-NOT transcription complex subunit 6-like; Carbon catabolite repressor protein 4 homolog B

Tested Applications

WB, IHC-P

Protein ID

166216089

Physical Properties

Liquid

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