ATP4B Antibody
Product Specifications
Background
ATP4B belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H (+) and K (+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase.
NCBI Gene ID
496
Swiss Prot
P51164
Accession Number
P51164
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This ATP4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-78 amino acids from the N-terminal region of human ATP4B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=61-824
Calculated Molecular Weight
33 kDa
Fragment
Rabbit Ig
Symbol
ATP4B
NCBI Official Name
Potassium-transporting ATPase subunit beta
NCBI Organism
Homo sapiens
Background Reference 01
Bab-Dinitz, E., et al. Biochemistry 48 (36) :8684-8691 (2009) Knouff, C.W., et al. Pharmacogenet. Genomics 18 (12) :1051-1057 (2008) Oh, J.H., et al. Mamm. Genome 16 (12) :942-954 (2005)
Other Product Names
Potassium-transporting ATPase subunit beta, Gastric H (+) /K (+) ATPase subunit beta, Proton pump beta chain, ATP4B
Tested Applications
WB, Flow
Protein ID
1703461
Physical Properties
Liquid
Curated Selection
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