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ENTPD8 Antibody

Product Specifications

Background

ENTPD8 is canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. It is ectonucleoside NTPDases catalyze the hydrolyzis of gamma-and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. ENTPD8 has activity toward ATP, ADP, UTP and UDP, but not toward AMP.

NCBI Gene ID

377841

Swiss Prot

Q5MY95

Accession Number

Q5MY95

Host

Rabbit

Reactivity

Human, Hamster

Immunogen

This ENTPD8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-423 amino acids from the C-terminal region of human ENTPD8.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

54 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ENTPD8

NCBI Official Name

Ectonucleoside triphosphate diphosphohydrolase 8

NCBI Organism

Homo sapiens

Background Reference 01

Munkonda, M.N., et al. Biochem. Pharmacol. 74 (10) :1524-1534 (2007)

Background Reference 02

Fausther, M., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 292 (3), G785-G795 (2007)

Background Reference 03

Knowles, A.F., et al. Biochemistry 45 (23) :7323-7333 (2006)

Other Product Names

Ectonucleoside triphosphate diphosphohydrolase 8, E-NTPDase 8, NTPDase 8, NTPDase8, ENTPD8

Tested Applications

WB

Protein ID

158705943

Physical Properties

Liquid

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