HSD17B2 Antibody

Product Specifications

Background

HSD17B2 is capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone.HSD17B2 also has 20-alpha-HSD activity. HSD17B2 uses NADH while EDH17B3 uses NADPH.

NCBI Gene ID

3294

Swiss Prot

P37059

Accession Number

P37059

Host

Rabbit

Reactivity

Human

Immunogen

This HSD17B2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-294 amino acids from the Central region of human HSD17B2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

43 kDa

Fragment

Rabbit Ig

Symbol

HSD17B2

NCBI Official Name

Estradiol 17-beta-dehydrogenase 2

NCBI Organism

Homo sapiens

Background Reference 01

Shen, Z., et al. Endocrinology 150 (11) :4941-4949 (2009)

Background Reference 02

Bhavani, V., et al. Cancer Biomark 5 (4) :207-213 (2009)

Background Reference 03

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Other Product Names

Estradiol 17-beta-dehydrogenase 2, 17-beta-hydroxysteroid dehydrogenase type 2, 17-beta-HSD 2, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, E2DH, Microsomal 17-beta-hydroxysteroid dehydrogenase, Testosterone 17-beta-dehydrogenase, HSD17B2, EDH17B2