JHDM1D Antibody
Product Specifications
Background
JHDM1D histone demethylase that specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3, thereby playing a central role in histone code. This specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. This demethylates H3K9me2 in absence of H3K4me3.
NCBI Gene ID
80853
Swiss Prot
Q6ZMT4
Accession Number
Q6ZMT4
Host
Rabbit
Reactivity
Human
Immunogen
This JHDM1D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-316 amino acids from the Central region of human JHDM1D.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=61-796
Calculated Molecular Weight
107 kDa
Fragment
Rabbit Ig
Symbol
KDM7A
NCBI Official Name
Lysine-specific demethylase 7A
NCBI Organism
Homo sapiens
Other Product Names
Lysine-specific demethylase 7A, 11411-, JmjC domain-containing histone demethylation protein 1D, Lysine-specific demethylase 7, KDM7A, JHDM1D, KDM7, KIAA1718
Tested Applications
WB, IHC-P, Flow
Protein ID
90111764
Physical Properties
Liquid
Curated Selection
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