NR5A1 Antibody

Product Specifications

Background

NR5A1 is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this protein are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect.

NCBI Gene ID

2516

Swiss Prot

Q13285

Accession Number

Q13285

Host

Rabbit

Reactivity

Human

Immunogen

This NR5A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-93 amino acids from the N-terminal region of human NR5A1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

52 kDa

Fragment

Rabbit Ig

Symbol

NR5A1

NCBI Official Name

Steroidogenic factor 1

NCBI Organism

Homo sapiens

Background Reference 01

Almeida, M.Q., et al. J. Clin. Endocrinol. Metab. 95 (3) :1458-1462 (2010)

Background Reference 02

Ramayya, M.S., et al. J. Steroid Biochem. Mol. Biol. 119 (1-2), 14-25 (2010)

Background Reference 03

Catalano, S., et al. J. Biol. Chem. 285 (8) :5581-5593 (2010)

Other Product Names

Steroidogenic factor 1, SF-1, STF-1, Adrenal 4-binding protein, Fushi tarazu factor homolog 1, Nuclear receptor subfamily 5 group A member 1, Steroid hormone receptor Ad4BP, NR5A1, AD4BP, FTZF1, SF1