NR5A1 Antibody
Product Specifications
Background
NR5A1 is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this protein are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect.
NCBI Gene ID
2516
Swiss Prot
Q13285
Accession Number
Q13285
Host
Rabbit
Reactivity
Human
Immunogen
This NR5A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-93 amino acids from the N-terminal region of human NR5A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
52 kDa
Fragment
Rabbit Ig
Symbol
NR5A1
NCBI Official Name
Steroidogenic factor 1
NCBI Organism
Homo sapiens
Background Reference 01
Almeida, M.Q., et al. J. Clin. Endocrinol. Metab. 95 (3) :1458-1462 (2010)
Background Reference 02
Ramayya, M.S., et al. J. Steroid Biochem. Mol. Biol. 119 (1-2), 14-25 (2010)
Background Reference 03
Catalano, S., et al. J. Biol. Chem. 285 (8) :5581-5593 (2010)
Other Product Names
Steroidogenic factor 1, SF-1, STF-1, Adrenal 4-binding protein, Fushi tarazu factor homolog 1, Nuclear receptor subfamily 5 group A member 1, Steroid hormone receptor Ad4BP, NR5A1, AD4BP, FTZF1, SF1
Tested Applications
WB, IHC-P, Flow
Protein ID
3121738
Physical Properties
Liquid
Frequently Asked Questions
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