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GLD2 Antibody

Product Specifications

Background

GLD2 is cytoplasmic poly (A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly (A) tail. In contrast to the canonical nuclear poly (A) RNA polymerase, it only adds poly (A) to selected cytoplasmic mRNAs. GLD2 does not play a role in replication-dependent histone mRNA degradation.

NCBI Gene ID

167153

Swiss Prot

Q6PIY7

Accession Number

Q6PIY7

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This GLD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-87 amino acids from the N-terminal region of human GLD2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

56 kDa

Fragment

Rabbit Ig

Symbol

PAPD4

NCBI Official Name

Poly (A) RNA polymerase GLD2

NCBI Organism

Homo sapiens

Background Reference 01

Mullen, T.E., et al. Genes Dev. 22 (1) :50-65 (2008) Kwak, J.E., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (13) :4407-4412 (2004)

Other Product Names

Poly (A) RNA polymerase GLD2, hGLD-2, PAP-associated domain-containing protein 4, Terminal uridylyltransferase 2, TUTase 2, PAPD4, GLD2

Tested Applications

WB, IHC-P, IF

Protein ID

74737798

Physical Properties

Liquid

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