What is the catalog number for XRCC6 Antibody?

The catalog number for XRCC6 Antibody is 61-786.

What sizes are available for XRCC6 Antibody?

XRCC6 Antibody is available in the following size(s): 400 µL.

Is XRCC6 Antibody in stock?

XRCC6 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

XRCC6 Antibody

Product Specifications

Background

XRCC6 is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V (D) J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

NCBI Gene ID

2547

Swiss Prot

P12956

Accession Number

P12956

Host

Rabbit

Reactivity

Human

Immunogen

This XRCC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 521-548 amino acids from the C-terminal region of human XRCC6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

70 kDa

Fragment

Rabbit Ig

Symbol

XRCC6

NCBI Official Name

X-ray repair cross-complementing protein 6

NCBI Organism

Homo sapiens

Background Reference 01

Vishnudas, V.K., et al. Hum. Mol. Genet. 18 (23) :4467-4477 (2009)

Background Reference 02

Wang, Q., et al. Neoplasia 11 (10) :1012-1021 (2009)

Background Reference 03

Beskow, C., et al. Br. J. Cancer 101 (5) :816-821 (2009)

Other Product Names

X-ray repair cross-complementing protein 6, 364-, 4299-, 5'-deoxyribose-5-phosphate lyase Ku70, 5'-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, DNA repair protein XRCC6, Lupus Ku autoantigen protein p70, Ku70, Thyroid-lupus autoantigen, TLAA, X-ray repair complementing defective repair in Chinese hamster cells 6, XRCC6, G22P1