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MIIP Antibody

Product Specifications

Background

MIIP inhibits glioma cells invasion and down-regulates adhesion-and motility-associated genes such as NFKB2 and ICAM1. MIIP exhibits opposing effects to IGFBP2 on cell invasion.

NCBI Gene ID

60672

Swiss Prot

Q5JXC2

Accession Number

Q5JXC2

Host

Rabbit

Reactivity

Human

Immunogen

This MIIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-303 amino acids from the C-terminal region of human MIIP.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

43 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MIIP

NCBI Official Name

Migration and invasion-inhibitory protein

NCBI Organism

Homo sapiens

Background Reference 01

Wu, Y., et al. J. Biol. Chem. 285 (6) :3554-3560 (2010) Song, F., et al. Cancer Res. 70 (3) :1024-1032 (2010) Hosgood, H.D. III, et al. Occup Environ Med 66 (12) :848-853 (2009)

Other Product Names

Migration and invasion-inhibitory protein, IGFBP2-binding protein, Invasion-inhibitory protein 45, IIp45, MIIP, IIP45

Tested Applications

WB

Protein ID

296439302

Physical Properties

Liquid

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