PMPCB Antibody
Product Specifications
Background
PMPCB is a member of the peptidase M16 family and encodes a protein with a zinc-binding motif. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria, though it only functions as part of a heterodimeric complex.
NCBI Gene ID
9512
Swiss Prot
O75439
Accession Number
O75439
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This PMPCB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the N-terminal region of human PMPCB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
54 kDa
Fragment
Rabbit Ig
Symbol
PMPCB
NCBI Official Name
Mitochondrial-processing peptidase subunit beta
NCBI Organism
Homo sapiens
Background Reference 01
Luczynski, W., et al. Neoplasma 56 (5) :428-434 (2009)
Background Reference 02
Schwer, B., et al. J. Cell Biol. 158 (4) :647-657 (2002)
Background Reference 03
Nagao, Y., et al. J. Biol. Chem. 275 (44) :34552-34556 (2000)
Other Product Names
Mitochondrial-processing peptidase subunit beta, Beta-MPP, P-52, PMPCB, MPPB
Tested Applications
WB, IHC-P, Flow
Physical Properties
Liquid
Frequently Asked Questions
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