GTD2A Antibody

Product Specifications

Background

GTD2A is unusual in that its coding sequence is mostly derived from Charlie8 repeat elements. However, there is mRNA and EST evidence to suggest that this gene is transcribed, and the encoded protein has a homolog in mouse, with which it shares 78% sequence identity. The exact function of this gene product is not known. It is inferred to be a transcription factor based on the presence of GTF2I-like repeats (containing helix-loop-helix motifs), also found in other proteins such as GTF2IRD1 and GTF2I. These three genes are clustered together on chr 7q11.23.

NCBI Gene ID

84163

Swiss Prot

Q86UP8

Accession Number

Q86UP8

Host

Rabbit

Reactivity

Human

Immunogen

This GTD2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 812-841 amino acids from the C-terminal region of human GTD2A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

107 kDa

Fragment

Rabbit Ig

Symbol

GTF2IRD2

NCBI Official Name

General transcription factor II-I repeat domain-containing protein 2A

NCBI Organism

Homo sapiens

Background Reference 01

Hinsley, T.A., et al. Protein Sci. 13 (10) :2588-2599 (2004)

Background Reference 02

Makeyev, A.V., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (30) :11052-11057 (2004)

Background Reference 03

Tipney, H.J., et al. Eur. J. Hum. Genet. 12 (7) :551-560 (2004)

Other Product Names

General transcription factor II-I repeat domain-containing protein 2A, GTF2I repeat domain-containing protein 2A, Transcription factor GTF2IRD2-alpha, GTF2IRD2, GTF2IRD2A