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PAH Antibody

Product Specifications

Background

PAH encodes the enzyme phenylalanine hydroxylase that is the rate-limiting step in phenylalanine catabolism. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria.

NCBI Gene ID

5053

Swiss Prot

P00439

Accession Number

P00439

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This PAH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-161 amino acids from the Central region of human PAH.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

52 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PAH

NCBI Official Name

Phenylalanine-4-hydroxylase

NCBI Organism

Homo sapiens

Background Reference 01

Bonyadi, M., et al. Genet Test Mol Biomarkers 14 (2) :233-235 (2010)

Background Reference 02

Dupuis, J., et al. Nat. Genet. 42 (2) :105-116 (2010)

Background Reference 03

Santos, L.L., et al. Genet. Mol. Res. 9 (1) :1-8 (2010)

Other Product Names

Phenylalanine-4-hydroxylase, PAH, Phe-4-monooxygenase, PAH

Tested Applications

WB

Protein ID

129973

Physical Properties

Liquid

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