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OPN1MW Antibody

Product Specifications

Background

OPN1MW encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called green cone photopigment or medium-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. The long-wavelength opsin gene and multiple copies of the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of deutanopic colorblindness.

NCBI Gene ID

1010602332652720000

Swiss Prot

P04001

Accession Number

P04001

Host

Rabbit

Reactivity

Human

Immunogen

This OPN1MW antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human OPN1MW.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat, Chicken, Xenopus

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

41 kDa

Fragment

Rabbit Ig

Symbol

OPN1MW

NCBI Official Name

Medium-wave-sensitive opsin 1

NCBI Organism

Homo sapiens

Background Reference 01

Thirumuruganandham, S.P., et al.Mol Model 15 (8) :959-969 (2009)

Background Reference 02

Ala-Laurila, P., et al. J. Biol. Chem. 284 (24) :16492-16500 (2009)

Background Reference 03

Holmes, M.V., et al. PLoS ONE (12), E7960 (2009)

Other Product Names

Medium-wave-sensitive opsin 1, Green cone photoreceptor pigment, Green-sensitive opsin, GOP, OPN1MW, GCP

Tested Applications

WB, Flow

Protein ID

129215

Physical Properties

Liquid

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