TNFRSF8-Y479 Antibody

Product Specifications

Background

TNFRSF8 is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.

NCBI Gene ID

943

Swiss Prot

P28908

Accession Number

P28908

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This TNFRSF8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 458-487 amino acids from human TNFRSF8.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

64 kDa

Fragment

Rabbit Ig

Symbol

TNFRSF8

NCBI Official Name

Tumor necrosis factor receptor superfamily member 8

NCBI Organism

Homo sapiens

Background Reference 01

Braun, F.K., et al. J. Invest. Dermatol. 130 (3) :826-840 (2010)

Background Reference 02

Azarpira, N., et al. SaudiKidney Dis Transpl 21 (1) :31-36 (2010)

Background Reference 03

Edinger, J.T., et al. Am. J. Surg. Pathol. 33 (12) :1860-1868 (2009)

Other Product Names

Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Ki-1 antigen, Lymphocyte activation antigen CD30, CD30, TNFRSF8, CD30, D1S166E

Tested Applications

WB, IHC-P

Protein ID

115978

Physical Properties

Liquid

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