NASP Antibody
Product Specifications
Background
NASP encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene. The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle. The testicular form is expressed in embryonic tissues, tumor cells, and the testis. In male germ cells, this protein is localized to the cytoplasm of primary spermatocytes, the nucleus of spermatids, and the periacrosomal region of mature spermatozoa.
NCBI Gene ID
4678
Swiss Prot
P49321
Accession Number
P49321
Host
Rabbit
Reactivity
Human
Immunogen
This NASP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the N-terminal region of human NASP.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
85 kDa
Fragment
Rabbit Ig
Symbol
NASP
NCBI Official Name
Nuclear autoantigenic sperm protein
NCBI Organism
Homo sapiens
Background Reference 01
Alekseev, O.M., et al. Reprod. Biol. Endocrinol. 7, 45 (2009)
Background Reference 02
Wang, H., et al. Nucleic Acids Res. 36 (18) :5763-5772 (2008)
Background Reference 03
Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)
Other Product Names
Nuclear autoantigenic sperm protein, NASP, NASP
Tested Applications
WB, Flow
Protein ID
23503077
Physical Properties
Liquid
Curated Selection
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