ATP2A1 Antibody
Product Specifications
Background
ATP2A1 encodes one of the SERCA Ca (2+) -ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction.
NCBI Gene ID
487
Swiss Prot
O14983
Accession Number
O14983
Host
Rabbit
Reactivity
Human
Immunogen
This ATP2A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 974-1001 amino acids from the C-terminal region of human ATP2A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rb
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=61-704
Calculated Molecular Weight
110 kDa
Fragment
Rabbit Ig
Symbol
ATP2A1
NCBI Official Name
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
NCBI Organism
Homo sapiens
Background Reference 01
Salanova, M., et al. Histochem. Cell Biol. 132 (4) :383-394 (2009)
Background Reference 02
Thorleifsson, G., et al. Nat. Genet. 41 (1) :18-24 (2009)
Background Reference 03
Chami, M., et al. Mol. Cell 32 (5) :641-651 (2008)
Other Product Names
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, SERCA1, SR Ca (2+) -ATPase 1, Calcium pump 1, Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform, Endoplasmic reticulum class 1/2 Ca (2+) ATPase, ATP2A1
Tested Applications
WB, IHC-P, Flow
Physical Properties
Liquid
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