ATP2A1 Antibody

Product Specifications

Background

ATP2A1 encodes one of the SERCA Ca (2+) -ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction.

NCBI Gene ID

487

Swiss Prot

O14983

Accession Number

O14983

Host

Rabbit

Reactivity

Human

Immunogen

This ATP2A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 974-1001 amino acids from the C-terminal region of human ATP2A1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rb

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

110 kDa

Fragment

Rabbit Ig

Symbol

ATP2A1

NCBI Official Name

Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

NCBI Organism

Homo sapiens

Background Reference 01

Salanova, M., et al. Histochem. Cell Biol. 132 (4) :383-394 (2009)

Background Reference 02

Thorleifsson, G., et al. Nat. Genet. 41 (1) :18-24 (2009)

Background Reference 03

Chami, M., et al. Mol. Cell 32 (5) :641-651 (2008)

Other Product Names

Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, SERCA1, SR Ca (2+) -ATPase 1, Calcium pump 1, Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform, Endoplasmic reticulum class 1/2 Ca (2+) ATPase, ATP2A1