YMEL1 Antibody

Product Specifications

Background

YMEL1 is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies.

NCBI Gene ID

10730

Swiss Prot

Q96TA2

Accession Number

Q96TA2

Host

Rabbit

Reactivity

Human, Hamster

Immunogen

This YMEL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-219 amino acids from the N-terminal region of human YMEL1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

86 kDa

Fragment

Rabbit Ig

Symbol

YME1L1

NCBI Official Name

ATP-dependent zinc metalloprotease YME1L1

NCBI Organism

Homo sapiens

Background Reference 01

Grupe, A., et al. Am. J. Hum. Genet. 78 (1) :78-88 (2006)

Background Reference 02

Deloukas, P., et al. Nature 429 (6990) :375-381 (2004)

Background Reference 03

Clark, H.F., et al. Genome Res. 13 (10) :2265-2270 (2003)

Other Product Names

ATP-dependent zinc metalloprotease YME1L1, 3424-, ATP-dependent metalloprotease FtsH1, Meg-4, Presenilin-associated metalloprotease, PAMP, YME1-like protein 1, YME1L1, FTSH1, YME1L