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PLA2G1B Antibody

Product Specifications

Background

PLA2G1B catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic PLA2 enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of PLA2 have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets

NCBI Gene ID

5319

Swiss Prot

P04054

Accession Number

P04054

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This PLA2G1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-145 amino acids from the C-terminal region of human PLA2G1B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

16 kDa

Fragment

Rabbit Ig

Symbol

PLA2G1B

NCBI Official Name

Phospholipase A2

NCBI Organism

Homo sapiens

Background Reference 01

Xu, W., et al. J. Biol. Chem. 284 (24) :16659-16666 (2009)

Background Reference 02

Han, C., et al. J. Cell. Biochem. 105 (2) :534-545 (2008)

Background Reference 03

Kao, W.T., et al. Lipids Health Dis 7, 20 (2008)

Other Product Names

Phospholipase A2, Group IB phospholipase A2, Phosphatidylcholine 2-acylhydrolase 1B, PLA2G1B, PLA2, PLA2A, PPLA2

Tested Applications

WB, Flow

Protein ID

129404

Physical Properties

Liquid

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