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TSPAN7 Antibody

Product Specifications

Background

TSPAN7 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy.

NCBI Gene ID

7102

Swiss Prot

P41732

Accession Number

P41732

Host

Rabbit

Reactivity

Human

Immunogen

This TSPAN7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-124 amino acids from the Central region of human TSPAN7.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

28 kDa

Fragment

Rabbit Ig

Symbol

TSPAN7

NCBI Official Name

Tetraspanin-7

NCBI Organism

Homo sapiens

Background Reference 01

Radhakrishnan, Y., et al. Biol. Reprod. 81 (4) :647-656 (2009)

Background Reference 02

Guilmatre, A., et al. Arch. Gen. Psychiatry 66 (9) :947-956 (2009)

Background Reference 03

Noor, A., et al. Psychiatr. Genet. 19 (3) :154-155 (2009)

Other Product Names

Tetraspanin-7, Tspan-7, Cell surface glycoprotein A15, Membrane component chromosome X surface marker 1, T-cell acute lymphoblastic leukemia-associated antigen 1, TALLA-1, Transmembrane 4 superfamily member 2, CD231, TSPAN7, A15, DXS1692E, MXS1, TM4SF2

Tested Applications

WB, Flow

Protein ID

17380550

Physical Properties

Liquid

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