TXNDC12 Antibody

Product Specifications

Background

TXNDC12 belongs to the thioredoxin superfamily (see TXN; MIM 187700) . Members of this superfamily possess a thioredoxin fold with a consensus active-site sequence (CxxC) and have roles in redox regulation, defense against oxidative stress, refolding of disulfide-containing proteins, and regulation of transcription factors

NCBI Gene ID

51060

Swiss Prot

O95881

Accession Number

O95881

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This TXNDC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-172 amino acids from the C-terminal region of human TXNDC12.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

19 kDa

Fragment

Rabbit Ig

Symbol

TXNDC12

NCBI Official Name

Thioredoxin domain-containing protein 12

NCBI Organism

Homo sapiens

Background Reference 01

Jessop, C.E., et al. J. Cell. Sci. 122 (PT 23), 4287-4295 (2009)

Background Reference 02

Rowe, M.L., et al. Biochemistry 48 (21) :4596-4606 (2009)

Background Reference 03

Jeong, W., et al. J. Biol. Chem. 283 (37) :25557-25566 (2008)

Other Product Names

Thioredoxin domain-containing protein 12, Endoplasmic reticulum resident protein 18, ER protein 18, ERp18, Endoplasmic reticulum resident protein 19, ER protein 19, ERp19, Thioredoxin-like protein p19, hTLP19, TXNDC12, TLP19