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DDX23 Antibody

Product Specifications

Background

DDX23 encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing.

NCBI Gene ID

9416

Swiss Prot

Q9BUQ8

Accession Number

Q9BUQ8

Host

Rabbit

Reactivity

Human

Immunogen

This DDX23 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-277 amino acids from the Central region of human DDX23.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=61-690

Calculated Molecular Weight

96 kDa

Fragment

Rabbit Ig

Symbol

DDX23

NCBI Official Name

Probable ATP-dependent RNA helicase DDX23

NCBI Organism

Homo sapiens

Background Reference 01

Mathew, R., et al. Nat. Struct. Mol. Biol. 15 (5) :435-443 (2008)

Background Reference 02

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007)

Background Reference 03

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Other Product Names

Probable ATP-dependent RNA helicase DDX23, 100 kDa U5 snRNP-specific protein, DEAD box protein 23, PRP28 homolog, U5-100kD, DDX23

Tested Applications

WB, IHC-P, Flow

Protein ID

160385708

Physical Properties

Liquid

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