TOX3 Antibody

Product Specifications

Background

TOX3 contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer.

NCBI Gene ID

27324

Swiss Prot

O15405

Accession Number

O15405

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This TOX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-242 amino acids from the Central region of human TOX3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

63 kDa

Fragment

Rabbit Ig

Symbol

TOX3

NCBI Official Name

TOX high mobility group box family member 3

NCBI Organism

Homo sapiens

Background Reference 01

Wacholder, S., et al. N. Engl. J. Med. 362 (11) :986-993 (2010)

Background Reference 02

Odefrey, F., et al. Cancer Res. 70 (4) :1449-1458 (2010)

Background Reference 03

Couch, F.J., et al. Cancer Epidemiol. Biomarkers Prev. 18 (11) :3044-3048 (2009)

Background Reference 04

Stacey, S.N., et al. Nat. Genet. 39 (7) :865-869 (2007)

Other Product Names

TOX high mobility group box family member 3, CAG trinucleotide repeat-containing gene F9 protein, Trinucleotide repeat-containing gene 9 protein, TOX3, CAGF9, TNRC9