SYTL2 Antibody
Product Specifications
Background
SYTL2 is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. The SLP homology domain (SHD) of this protein has been shown to specifically bind the GTP-bound form of Ras-related protein Rab-27A (RAB27A) . This protein plays a role in RAB27A-dependent vesicle trafficking and controls melanosome distribution in the cell periphery.
NCBI Gene ID
54843
Swiss Prot
Q9HCH5
Accession Number
Q9HCH5
Host
Rabbit
Reactivity
Human
Immunogen
This SYTL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 840-868 amino acids from the Central region of human SYTL2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
105 kDa
Fragment
Rabbit Ig
Symbol
SYTL2
NCBI Official Name
Synaptotagmin-like protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Menasche, G., et al. Blood 112 (13) :5052-5062 (2008)
Background Reference 02
Kesari, A., et al. Am. J. Pathol. 173 (5) :1476-1487 (2008)
Background Reference 03
Chavas, L.M., et al. Structure 16 (10) :1468-1477 (2008)
Other Product Names
Synaptotagmin-like protein 2, Breast cancer-associated antigen SGA-72M, Exophilin-4, SYTL2, KIAA1597, SGA72M, SLP2, SLP2A
Tested Applications
WB, IHC-P, Flow
Protein ID
257051068
Physical Properties
Liquid
Curated Selection
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