ZO1 Antibody
Product Specifications
Background
ZO1 encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions.
NCBI Gene ID
7082
Swiss Prot
Q07157
Accession Number
Q07157
Host
Rabbit
Reactivity
Human
Immunogen
This ZO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1570-1600 amino acids from the C-terminal region of human ZO1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
195 kDa
Fragment
Rabbit Ig
Symbol
TJP1
NCBI Official Name
Tight junction protein ZO-1
NCBI Organism
Homo sapiens
Background Reference 01
Ohira, M., et al. Int. J. Mol. Med. 24 (6) :829-835 (2009)
Background Reference 02
Hirakawa, H., et al. Int. J. Oncol. 35 (6) :1271-1276 (2009)
Background Reference 03
Meerschaert, K., et al. Cell. Mol. Life Sci. 66 (24) :3951-3966 (2009)
Background Reference 04
Kirschner, N., et al. Am. J. Pathol. 175 (3) :1095-1106 (2009)
Other Product Names
Tight junction protein ZO-1, Tight junction protein 1, Zona occludens protein 1, Zonula occludens protein 1, TJP1, ZO1
Tested Applications
WB, IHC-P, Flow
Protein ID
85700443
Physical Properties
Liquid
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