ZO1 Antibody

Product Specifications

Background

ZO1 encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions.

NCBI Gene ID

7082

Swiss Prot

Q07157

Accession Number

Q07157

Host

Rabbit

Reactivity

Human

Immunogen

This ZO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1570-1600 amino acids from the C-terminal region of human ZO1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

195 kDa

Fragment

Rabbit Ig

Symbol

TJP1

NCBI Official Name

Tight junction protein ZO-1

NCBI Organism

Homo sapiens

Background Reference 01

Ohira, M., et al. Int. J. Mol. Med. 24 (6) :829-835 (2009)

Background Reference 02

Hirakawa, H., et al. Int. J. Oncol. 35 (6) :1271-1276 (2009)

Background Reference 03

Meerschaert, K., et al. Cell. Mol. Life Sci. 66 (24) :3951-3966 (2009)

Background Reference 04

Kirschner, N., et al. Am. J. Pathol. 175 (3) :1095-1106 (2009)

Other Product Names

Tight junction protein ZO-1, Tight junction protein 1, Zona occludens protein 1, Zonula occludens protein 1, TJP1, ZO1

Tested Applications

WB, IHC-P, Flow

Protein ID

85700443

Physical Properties

Liquid

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