BHLHB5 Antibody

Product Specifications

Background

BHLHB5 inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47) /NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. BHLHB5 despite the presence of an intact basic domain, does not bind to DNA.

NCBI Gene ID

27319

Swiss Prot

Q8NFJ8

Accession Number

Q8NFJ8

Host

Rabbit

Reactivity

Human

Immunogen

This BHLHB5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-264 amino acids from the Central region of human BHLHB5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Chicken, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

37 kDa

Fragment

Rabbit Ig

Symbol

BHLHE22

NCBI Official Name

Class E basic helix-loop-helix protein 22

NCBI Organism

Homo sapiens

Background Reference 01

Stevens, J.D., et al. Differentiation 76 (9) :1006-1022 (2008)

Background Reference 02

McLellan, A.S., et al. Mech. Dev. 119 SUPPL 1, S285-S291 (2002)

Other Product Names

Class E basic helix-loop-helix protein 22, bHLHe22, Class B basic helix-loop-helix protein 5, bHLHb5, Trinucleotide repeat-containing gene 20 protein, BHLHE22, BHLHB5, TNRC20