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SAC2 Antibody

Product Specifications

Background

SAC2 is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants have been observed, but most of them are not thought to be protein-coding.

NCBI Gene ID

22876

Swiss Prot

Q9Y2H2

Accession Number

Q9Y2H2

Host

Rabbit

Reactivity

Human

Immunogen

This SAC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-161 amino acids from the N-terminal region of human SAC2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

128 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

INPP5F

NCBI Official Name

Phosphatidylinositide phosphatase SAC2

NCBI Organism

Homo sapiens

Background Reference 01

Zhu, W., et al. Circ. Res. 105 (12) :1240-1247 (2009)

Background Reference 02

Thole, J.M., et al. Plant Cell 20 (2) :381-395 (2008)

Background Reference 03

Grupe, A., et al. Am. J. Hum. Genet. 78 (1) :78-88 (2006)

Other Product Names

Phosphatidylinositide phosphatase SAC2, 313-, Inositol polyphosphate 5-phosphatase F, Sac domain-containing inositol phosphatase 2, Sac domain-containing phosphoinositide 5-phosphatase 2, hSAC2, INPP5F, KIAA0966, SAC2

Tested Applications

WB

Protein ID

187611527

Physical Properties

Liquid

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