CJ119 Antibody

Product Specifications

Background

CJ119 is a carefully orchestrated process involving many proteins that assemble at origins of replication. Among these are the 6 proteins of the minichromosome maintenance (MCM) complex (e.g., MCM2; MIM 116945), which form a hexamer. Each MCM subunit performs an essential function in initiation and elongation of DNA replication. MCMBP can replace MCM2 in the MCM complex, thus forming an alternative MCM hexamer.

NCBI Gene ID

79892

Swiss Prot

Q9BTE3

Accession Number

Q9BTE3

Host

Rabbit

Reactivity

Human

Immunogen

This CJ119 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-171 amino acids from the N-terminal region of human CJ119.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

73 kDa

Fragment

Rabbit Ig

Symbol

MCMBP

NCBI Official Name

Mini-chromosome maintenance complex-binding protein

NCBI Organism

Homo sapiens

Background Reference 01

Takahashi, N., et al. PLoS Genet. (1), E1000817 (2010)

Background Reference 02

Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)

Background Reference 03

Sakwe, A.M., et al. Mol. Cell. Biol. 27 (8) :3044-3055 (2007)

Other Product Names

Mini-chromosome maintenance complex-binding protein, MCM-BP, MCM-binding protein, MCMBP, C10orf119

Tested Applications

WB, IHC-P, Flow

Protein ID

71153001

Physical Properties

Liquid

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